YBX1 Recombinant Rabbit Monoclonal Antibody (9J7M4)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA542819 | 100 µL | 558,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Positive test controls include: Mouse testis, Rat heart, HeLa. The target is usually found in the following locations: Cytoplasm, Cytoplasmic granule, Nucleus, Secreted. YBX1 binds to splice sites in pre-mRNA and regulates splice site selection. This protein binds and stabilizes cytoplasmic mRNA and contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors. It binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as HLA class II genes. It regulates the transcription of numerous genes and promotes separation of DNA strands that contain mismatches or are modified by cisplatin. It has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro), and it may play a role in DNA repair.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ChIP, ICC, IHC, IP, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 225-324 of human YB-1/YBX1 (P67809). |
| Host | Rb |
| Clone Number | [9J7M4] |
| Genebank | YBX1 |
| Isotype | IgG |
| Crossreactivity | Hu, Ms, Rt |
| Clonality | Recombi |
| Format | Liquid; PBS; pH 7.3, with 0.05% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 0.5 mg/mL |
| Working Dilution | Immunocytochemistry (1:50 - 1:200), Immunohistochemistry (Paraffin) (1:50-1:200), Immunoprecipita... |
| Purity | Affinity Chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: MA5-42819 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Ambient |
| Material Safety Data Sheet | Download PDF |
