IL4R Recombinant Rabbit Monoclonal Antibody (R001)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA543118 | 200 µg | 572,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Specificity: Human IL-4R/CD124 IL4 Receptor alpha (IL4RA) is the alpha chain of the interleukin 4 receptor which binds to both interleukin 4 and interleukin 13 to regulate IgE production, chemokine and mucus production at sites of allergic inflammmation. The IL4 response is involved in promoting Th2 differentiation. The secreted extracellular domain of IL4R alpha, called sIL4R alpha, can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. It has no signaling abilities. Allelic variations in the IL4RA gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | N |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | Recombinant Human IL-4R/CD124 Protein. |
| Host | Rb |
| Clone Number | [R001] |
| Genebank | IL4R |
| Isotype | IgG |
| Crossreactivity | Hu |
| Clonality | Recombi |
| Format | Liquid; 0.2µM Buffered saline solution; , with 0.02% Tween 80 and no preservative |
| Concentration | 1 mg/mL |
| Working Dilution | Neutralization (0.2 ng/mL) |
| Purity | Protein A |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: MA5-43118 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Ambient |
| Material Safety Data Sheet | Download PDF |
