CD100 (SEMA4D) Recombinant Human Monoclonal Antibody (21E8)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA543159 | 100 µL | 532,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Antibody tested in Indirect ELISA Semaphorins are neuronal chemorepellants that direct pioneering neurons during nervous system development. CD100 (also known as semaphorin 4d), a 150 kDa homodimer, is a novel semaphorin that induces B cells to aggregate and improves their viability in vitro. CD100 modifies CD40-CD40L B cell signaling by augmenting B cell aggregation and survival and down regulating CD23 expression. CD72 is a lymphocyte receptor for the class IV semaphorin CD100, which is involved in regulating B cell signaling. CD100 is expressed on resting and PHA stimulated T cells. The protein is weakly expressed on NK cells, EBV transformed B cells, monocytes and tumor/peripheral blood T cell lines, and at higher density on activated T cells and B cells.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | EL, FC |
| Regulatory Status | RUO |
| Immunogen | Recombinant Human SEMA4D protein |
| Host | Hu |
| Clone Number | [21E8] |
| Genebank | SEMA4D |
| Isotype | IgG4 |
| Crossreactivity | Hu |
| Clonality | Recombi |
| Format | Liquid; PBS; pH 7.4, with 50% glycerol and 0.03% ProClin 300 |
| Concentration | 1 mg/mL |
| Working Dilution | Flow Cytometry (1:50-1:200), ELISA (Assay-dependent) |
| Purity | Affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | -20°C or -80°C if preferred |
| Disclaimer | Alternative CatNo: MA5-43159 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
