HFE2 Monoclonal Antibody (A7)
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MA543775 | 20 µL | 200,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
HFE2 is involved in iron metabolism. It may be a component of the signaling pathway which activates hepcidin or it may act as a modulator of hepcidin expression. It could also represent the cellular receptor for hepcidin. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Defects in this gene are the cause of hemochromatosis type 2A, also called juvenile hemochromatosis (JH). JH is an early-onset autosomal recessive disorder due to severe iron overload resulting in hypogonadotrophic hypogonadism, hepatic fibrosis or cirrhosis and cardiomyopathy, occurring typically before age of 30.
Category | Antibody |
Supplier | ThermoFisher |
Application | ICC, IHC, WB |
Regulatory Status | RUO |
Immunogen | Recombinant protein Hemojuvelin. The antigen corresponds to amino acid range 29-401 of the target protein. |
Host | Ms |
Clone Number | [A7] |
Genebank | HFE2 |
Isotype | IgG2b,l |
Crossreactivity | Hu |
Clonality | Mab |
Format | Liquid; PBS; , with 50% glycerol and 0.05% ProClin 300 |
Concentration | 1 mg/mL |
Working Dilution | Western Blot (0.5-3 µg/mL), Immunocytochemistry (5-30 µg/mL), Immunohistochemistry (Paraffin) (5-... |
Purity | Protein A/G |
Conjugation | Unconjugated |
Storage Conditions | -20°C |
Disclaimer | Alternative CatNo: MA5-43775 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |