Insulin Monoclonal Antibody (IN-05)
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MA544059 | 100 µg | 347,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Functional application: The antibody blocks binding of insulin to the receptor Insulin is a peptide hormone secreted by beta cells of the pancreatic islets. It regulates carbohydrate, protein and lipid metabolism by enhancing membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Insulin is 51-amino acid polypeptide product produced from a precursor peptide, proinsulin. Proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds and one molecule of C-peptide. Insulin deficiency results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of b-cell origin such as insulinoma.
Category | Antibody |
Supplier | ThermoFisher |
Application | EL, ICC, IHC, RIA |
Regulatory Status | RUO |
Immunogen | Porcine insulin. |
Host | Ms |
Clone Number | [IN-05] |
Genebank | INS |
Isotype | IgG1 |
Crossreactivity | Bo, Hu, Pg |
Clonality | Mab |
Format | Liquid; PBS; pH 7.4, with no preservative |
Concentration | 1 mg/mL |
Working Dilution | ELISA (Assay-dependent), Functional Assay (Assay-dependent), Immunocytochemistry (Assay-dependent... |
Purity | Protein A |
Conjugation | Unconjugated |
Storage Conditions | 4° C, do not freeze |
Disclaimer | Alternative CatNo: MA5-44059 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |