alpha/beta Tubulin Monoclonal Antibody (TU-10), Alexa Fluor™ 488
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MA544130 | 100 µg | 437,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Tubulin protein is the major constituent of microtubules. Tubulin is a dimer of alpha and beta chains, which binds two molecules of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. There are at least six isotypes of both alpha- and beta- tubulin in human cells, which are distinguished by slightly different amino acid sequences and encoded by a large, multigene family that has been highly conserved throughout evolution. Although the most important functions of microtubules in proliferative cells are through their actions as components of the mitotic spindle, they are also involved in many other essential functions throughout the cell cycle of both malignant and nonmalignant cells. Anti-microtubule agents including Vinca alkaloids and taxanes may disrupt many of these essential functions.
Category | Antibody |
Supplier | ThermoFisher |
Application | FC, ICC, WB |
Regulatory Status | RUO |
Immunogen | Microtubule proteins from porcine brain |
Host | Ms |
Clone Number | [TU-10] |
Genebank | TUBA1A |
Isotype | IgM |
Crossreactivity | Hu, Ms, Primate, Pg, Rt |
Clonality | Mab |
Format | Liquid; TBS; pH 8, with 0.2% BSA and 15mM sodium azide |
Concentration | 0.1 mg/mL |
Working Dilution | Flow Cytometry (1-4 µg/mL), Immunocytochemistry (Assay-dependent), Western Blot (Assay-dependent) |
Purity | Size-exclusion chromatography |
Conjugation | Alexa Fluor 488 |
Storage Conditions | 4° C, store in dark, DO NOT FREEZE! |
Disclaimer | Alternative CatNo: MA5-44130 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |