CTLA-4 Monoclonal Antibody (BNI3), Alexa Fluor™ 647
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA544148 | 100 Tests | 438,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor expressed on mainly CD4+ T cells. It binds the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells), but with higher affinity than CD28. However, in contrast to CD28 which enhances cell function when bound at the same time as the T cell receptor, CTLA4 inhbits the T cell and prevents it from functioning. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | FC, ICC |
| Regulatory Status | RUO |
| Immunogen | Human CD152-IgG heavy chain fusion protein |
| Host | Ms |
| Clone Number | [BNI3] |
| Genebank | CTLA4 |
| Isotype | IgG2a |
| Crossreactivity | Hu |
| Clonality | Mab |
| Format | Liquid; PBS; pH 7.4, with 0.2% BSA and 15mM sodium azide |
| Working Dilution | Immunocytochemistry (Assay-dependent), Flow Cytometry (4 µL/1x10^6 cells) |
| Purity | Size-exclusion chromatography |
| Conjugation | Alexa Fluor 647 |
| Storage Conditions | 4° C, store in dark, DO NOT FREEZE! |
| Disclaimer | Alternative CatNo: MA5-44148 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
