HSP70 Monoclonal Antibody (C92F3A-5), PerCP
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MA545092 | 200 µg | 429,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
HSP70 is a Heat shock protein (HSP) which are expressed in response to various biological stresses, including high temperatures. There are several major families of HSPs that include HSP70, there are HSP90 and HSP100. The HSP70 family is a set of highly conserved proteins that are induced by a variety of biological stresses, including heat stress, in every organism in which the proteins have been examined. The human HSP70 family members include: HSP70, a protein which is strongly inducible in all organisms but which is also constitutively expressed in primate cells; HSP72, a 72 kDa protein that is induced exclusively under stress conditions; HSC70, or cognate protein, is a 72 kDa, constitutively expressed, protein which is involved in the uncoating of clathrin coated vesicles; GRP78, or BiP, is a glucose regulated 78 kDa protein localized in the endoplasmic reticulum; and p75, or HSP75, a 75 kDa protein that is found within the mitochondria. Further, HSP70 is encoded by an intronless gene and, in conjunction with other heat shock proteins, HSP70 stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and organelles. HSP70 is also involved in the ubiquitin-proteasome pathway through interaction with the
Category | Antibody |
Supplier | ThermoFisher |
Application | EL, FC, ICC, IHC, WB |
Regulatory Status | RUO |
Immunogen | Human HSP70 |
Host | Ms |
Clone Number | [C92F3A-5] |
Genebank | HSPA1A |
Isotype | IgG1 |
Crossreactivity | Bo, C.elegans, Dg, Ck, Drosophila, Fish, Gp, Hm, Hu, Monkey, Ms, Sh, Pg, Rb, Rt |
Clonality | Mab |
Format | Liquid; 2.15mM MES, 47.35mM phosphate; pH 7.4, with 1.033mM EDTA and no preservative |
Concentration | 1 mg/mL |
Working Dilution | ELISA (Assay-dependent), Flow Cytometry (1:1,000), Inhibition Assays (Assay-dependent), Immunocyt... |
Purity | Protein G |
Conjugation | PerCP |
Storage Conditions | 4° C |
Disclaimer | Alternative CatNo: MA5-45092 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |