GRP94 Monoclonal Antibody (9G10), APC
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA545096 | 200 µg | 467,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
GRP94 is a 803 amino acid protein belonging to the heat shock protein 90 family. It acts as a molecular chaperone that functions in the processing and transport of secreted proteins. GRP94 and its N-terminal fragment stimulates CTL expansion and maturation of human monocyte-derived dendritic cells (MDDC). It plays a central role in innate as well as acquired immunity, maturation and chemotaxis of dendritic cells, Ab production, cross-priming, as a potential marker in breast cancer and is a peptide acceptor in endoplasmic reticulum and an accessory to peptide loading of MHC class I molecules. Expression of GRP94 suppressed A23187-induced apoptosis and stabilized calcium homeostasis. GRP94 is expressed in melanoma or liver metastases of colon carcinoma cells, human gastric carcinoma BGC-823 cells.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | FC, ICC, IP, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | Purified Grp94 isolated from chicken oviducts |
| Host | Rt |
| Clone Number | [9G10] |
| Genebank | HSP90B1 |
| Isotype | IgG2a |
| Crossreactivity | Bo, Dg, Ck, Ho, Gp, Hm, Hu, Monkey, Ms, Sh, Pg, Rb, Rt, Xenopus |
| Clonality | Mab |
| Format | Liquid; 2.15mM MES, 47.35mM phosphate; pH 7.2, with 1.033mM EDTA and no preservative |
| Concentration | 1 mg/mL |
| Working Dilution | Flow Cytometry (Assay-dependent), Immunocytochemistry (1:100), Immunoprecipitation (Assay-depende... |
| Purity | Protein G |
| Conjugation | APC |
| Storage Conditions | Cold Room (2 to 8 C) |
| Disclaimer | Alternative CatNo: MA5-45096 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Ambient |
| Material Safety Data Sheet | Download PDF |
