GRP94 Monoclonal Antibody (9G10), APC
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MA545096 | 200 µg | 415,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
GRP94 is a 803 amino acid protein belonging to the heat shock protein 90 family. It acts as a molecular chaperone that functions in the processing and transport of secreted proteins. GRP94 and its N-terminal fragment stimulates CTL expansion and maturation of human monocyte-derived dendritic cells (MDDC). It plays a central role in innate as well as acquired immunity, maturation and chemotaxis of dendritic cells, Ab production, cross-priming, as a potential marker in breast cancer and is a peptide acceptor in endoplasmic reticulum and an accessory to peptide loading of MHC class I molecules. Expression of GRP94 suppressed A23187-induced apoptosis and stabilized calcium homeostasis. GRP94 is expressed in melanoma or liver metastases of colon carcinoma cells, human gastric carcinoma BGC-823 cells.
Category | Antibody |
Supplier | ThermoFisher |
Application | FC, ICC, IP, WB |
Regulatory Status | RUO |
Immunogen | Purified Grp94 isolated from chicken oviducts |
Host | Rt |
Clone Number | [9G10] |
Genebank | HSP90B1 |
Isotype | IgG2a |
Crossreactivity | Bo, Dg, Ck, Ho, Gp, Hm, Hu, Monkey, Ms, Sh, Pg, Rb, Rt, Xenopus |
Clonality | Mab |
Format | Liquid; 2.15mM MES, 47.35mM phosphate; pH 7.2, with 1.033mM EDTA and no preservative |
Concentration | 1 mg/mL |
Working Dilution | Flow Cytometry (Assay-dependent), Immunocytochemistry (1:100), Immunoprecipitation (Assay-depende... |
Purity | Protein G |
Conjugation | APC |
Storage Conditions | 4° C |
Disclaimer | Alternative CatNo: MA5-45096 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |