HSP27 Monoclonal Antibody (8A7), APC
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MA545121 | 100 µg | 376,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
In response to adverse changes in their environment, cells from many organisms increase the expression of a class of proteins referred to as heat shock or stress proteins. HSPB1 (heat shock protein beta-1 or HSP27) is a small heat shock protein which functions as a molecular chaperone that maintains denatured proteins in a folding-competent state. It plays a role in stress resistance and actin organization. Through its molecular chaperone activity, HSP27 regulates numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins. Mutations in the gene can result in Charcot-Marie-Tooth disease 2F and Neuronopathy distal hereditary motor 2B.
Category | Antibody |
Supplier | ThermoFisher |
Application | FC, ICC, IHC, IP, WB |
Regulatory Status | RUO |
Immunogen | HSP27 peptide |
Host | Ms |
Clone Number | [8A7] |
Genebank | HSPB1 |
Isotype | IgG1,k |
Crossreactivity | Bo, Dg, Gp, Hm, Hu, Ms, Sh, Rt |
Clonality | Mab |
Format | Liquid; 2.15mM MES, 47.35mM phosphate; , with 1.033mM EDTA and no preservative |
Concentration | 1 mg/mL |
Working Dilution | Immunohistochemistry (PFA fixed) (1:5,000), Immunoprecipitation (Assay-dependent), Western Blot (... |
Purity | Protein G |
Conjugation | APC |
Storage Conditions | 4° C |
Disclaimer | Alternative CatNo: MA5-45121 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |