CaMKII alpha Monoclonal Antibody (6G9), APC
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA545143 | 100 µg | 376,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
The Ca2+/calmodulin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine/threonine kinases which include CaMKI, CaMKII and CaMKIV. CaMKII is an ubiquitously expressed serine/threonine protein kinase that is activated by Ca2+/calmodulin (CaM) binding and autophosphorylation and has been implicated in regulation of the cell cycle and transcription. It is involved in dendritic spine and synapse formation, neuronal plasticity and regulation of sarcoplasmic reticulum Ca2+ transport in skeletal muscle. In neurons, plays an essential structural role in the reorganization of the actin cytoskeleton during plasticity by binding and bundling actin filaments in a kinase-independent manner.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | EL, ICC, IHC, IP, RIA, WB |
| Regulatory Status | RUO |
| Immunogen | Partially purified rat CaMKII |
| Host | Ms |
| Clone Number | [6G9] |
| Genebank | CAMK2A |
| Isotype | IgG1 |
| Crossreactivity | Bo, Hu, Ms, Rt |
| Clonality | Mab |
| Format | Liquid; 2.15mM MES, 47.35mM phosphate; pH 7.2, with 1.033mM EDTA and no preservative |
| Concentration | 1 mg/mL |
| Working Dilution | ELISA (Assay-dependent), Immunocytochemistry (1:50), Immunohistochemistry (Paraffin) (1:100), Imm... |
| Purity | Protein G |
| Conjugation | APC |
| Storage Conditions | 4° C |
| Disclaimer | Alternative CatNo: MA5-45143 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
