CaV1.2 Monoclonal Antibody (S57), APC
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA545387 | 100 µg | 406,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
CACNA1C encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by CACNA1C binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ICC, IHC, IP, WB |
| Regulatory Status | RUO |
| Immunogen | Fusion protein amino acids 1507-1733 (intracellular carboxyl terminus) of rabbit Cav1.2 |
| Host | Ms |
| Clone Number | [S57] |
| Genebank | CACNA1C |
| Isotype | IgG1 |
| Crossreactivity | Hm, Hu, Ms, Rt |
| Clonality | Mab |
| Format | Liquid; 2.15mM MES, 47.35mM phosphate; pH 7.4, with 1.033mM EDTA and no preservative |
| Concentration | 1 mg/mL |
| Working Dilution | Immunocytochemistry (1:100), Immunohistochemistry (PFA fixed) (1:100), Immunoprecipitation (1:200... |
| Purity | Protein G |
| Conjugation | APC |
| Storage Conditions | 4° C |
| Disclaimer | Alternative CatNo: MA5-45387 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
