TCP1 Monoclonal Antibody (23c), FITC
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA545716 | 100 µg | 376,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
The T Complex Polypeptide 1 (TCP-1) is approximately 60 kDa protein constitutively expressed in almost all eukaryotic cells, and is upregulated during spermatogenesis. It is found in the cytosol as a subunit of a hetero-oligomeric chaperone that is known to be involved in the folding of actin and tubulin. The family of proteins termed chaperonins act to recognize and stabilize polypeptide intermediates during folding, assembly and disassembly, and share many characteristics with Heat Shock Protein 70 (HSP70) including high abundance, induction by environmental stress, and ATPase activity. The chaperonin family includes the mitochondrial HSP60, Escherichia coli GroEL, the plastid Rubisco-subunit binding protein, and the archaebacterial protein TF55. The TCP-1 sequence shows nearly 40% identity to TF55, but only minimal similarity to HSP60 and GroEL.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ICC, IP, WB |
| Regulatory Status | RUO |
| Immunogen | Purified recombinant mouse TCP1 alpha construct encoding the C-terminal half of the 1.8 kb full-length Tcp 1b gene expressed in E. coli. Detects the COOH group. |
| Host | Rt |
| Clone Number | [23c] |
| Genebank | TCP1 |
| Isotype | IgG2c |
| Crossreactivity | Bo, Dg, Hm, Hu, Ms, Sh, Rb, Rt |
| Clonality | Mab |
| Format | Liquid; 9.1mM sodium bicarbonate, 9.44mM PBS; pH 7.4, with 123mM ethanolamine, 581mM DMSO and no preservative |
| Concentration | 1 mg/mL |
| Working Dilution | Immunocytochemistry (1:100), Immunoprecipitation (Assay-dependent), Western Blot (1:1,000) |
| Purity | Protein G |
| Conjugation | FITC |
| Storage Conditions | 4° C, store in dark |
| Disclaimer | Alternative CatNo: MA5-45716 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
