NDFIP1 Monoclonal Antibody (N1Nterm15-328)


Catalog Number Pack Size List Price* Quantity
MA546562 50 µg 327,00 Add

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Product Description

The NEDD4 family-interacting protein 1 (NDFIP1) belongs to a small group of evolutionarily conserved proteins with three transmembrane domains and is an integral Golgi membrane protein. It is a potential target for ubiquitination by the Nedd4 family of proteins. NDFIP1 is strongly expressed in surviving neurons following acute cortical brain injury, and overexpression in cultured cortical neurons increased survival following growth factor starvation, suggesting that NDFIP1 may play a role in neuronal survival. NDFIP1 and the related protein NDFIP2 are thought to interact with and regulate multiple components of the EGF and PTEN/Akt signaling pathways. Recent studies suggest that NDFIP1 may also play a role in Th17 differentiation by limiting the production of proinflammatory cytokines.

Category Antibody
Supplier ThermoFisher
Application EL, WB
Regulatory Status RUO
Immunogen N-terminal peptide of murine Ndfip 1 coupled to KLH (VEPACGSGYQQLQNEEPGE)
Host Hm
Clone Number [N1Nterm15-328]
Genebank NDFIP1
Isotype IgG2b
Crossreactivity Ms
Clonality Mab
Format Liquid; PBS; , with 0.1% sodium azide
Concentration 1 mg/mL
Working Dilution ELISA (Assay-dependent), Western Blot (1:500)
Purity Protein G
Conjugation Unconjugated
Storage Conditions Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Disclaimer Alternative CatNo: MA5-46562
Tech. Data Sheet View datasheet
Link To Supplier https://www.thermofisher.com
Material Safety Data Sheet Download PDF