B-Raf Recombinant Rabbit Monoclonal Antibody (HL1606)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA547108 | 100 μL | 464,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Store as concentrated solution. Centrifuge briefly prior to opening vial. B-raf belongs to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in the gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ICC, IHC, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human B-Raf. The exact sequence is proprietary. |
| Host | Rb |
| Clone Number | [HL1606] |
| Genebank | BRAF |
| Isotype | IgG |
| Crossreactivity | Dg, Ca, Hu, Ms, Rt |
| Clonality | Mab |
| Format | Liquid; PBS; , with no preservative |
| Concentration | 1 mg/mL |
| Working Dilution | Immunocytochemistry (Assay-dependent), Immunohistochemistry (Paraffin) (Assay-dependent), Western... |
| Purity | Protein A |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: MA5-47108 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Ambient |
| Material Safety Data Sheet | Download PDF |
