PIK3C2A Recombinant Rabbit Monoclonal Antibody (HL1612)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA547109 | 100 μL | 464,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Store as concentrated solution. Centrifuge briefly prior to opening vial. The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | IHC, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human PI3 kinase C2 alpha. The exact sequence is proprietary. |
| Host | Rb |
| Clone Number | [HL1612] |
| Genebank | PIK3C2A |
| Isotype | IgG |
| Crossreactivity | Dg, Ca, Hu, Ms, Rt |
| Clonality | Mab |
| Format | Liquid; PBS; , with no preservative |
| Concentration | 1 mg/mL |
| Working Dilution | Immunohistochemistry (Paraffin) (Assay-dependent), Western Blot (1:500-1:3,000) |
| Purity | Protein A |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: MA5-47109 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Ambient |
| Material Safety Data Sheet | Download PDF |
