IFN gamma Monoclonal Antibody (CC302)

* CHF, excl. 8.1% VAT and shipping costs

Product Description

MBOIFNG targets IFN gamma in ELISA, and FACS applications and shows reactivity with Bovine, Canine, Equine, Goat, Human, Mustelid, Ovine, and Porcine samples. The MBOIFNG immunogen is recombinant Bovine IFN gamma. MBOIFNG detects IFN gamma which has a predicted molecular weight of approximately 17 kDa. IFN gamma (Interferon gamma, Type II interferon) is a macrophage activation factor, and immune interferon that is produced primarily by T-lymphocytes and natural killer cells in response to antigens, mitogens, Staphylococcus enterotoxin B, phytohemaglutanin and other cytokines. IFN gamma is a dimeric protein consisting of two 146 amino acid subunits. IFN gamma is a glycoprotein that exists, functionally, as a homodimer of approximately 45 kDa. On SDS-PAGE, IFN gamma appears as a combination of 25, 20 and minor 15.5 kDa bands as a result of differential glycosylation. The biological activity of the IFN gamma homodimer is highly species specific. Human IFN gamma does not show cross-reactivity with mouse. IFN gamma function includes the following: antiviral activity, tumor antiproliferative activity, induction of class I and II MHC, macrophage activation, and enhanced immunoglobulin secretion by B lymphocytes. IFN gamma is involved in cytokine regulation and also acts