CD4 Monoclonal Antibody (S3.5), PE-Texas Red
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MHCD0417 | 500 µL | 740,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
The R-phycoerythrin (PE)-Texas Red conjugate permits simultaneous multicolor labeling and detection of multiple targets with excitation by a single excitation source-the 488 nm line of the argon-ion laser. The CD4 antigen is involved in the recognition of MHC class II molecules and is a co-receptor for HIV. CD4 is primarily expressed in a subset of T-lymphocytes, also referred to as T helper cells, but may also be expressed by other cells in the immune system, such as monocytes, macrophages, and dendritic cells. At the tissue level, CD4 expression may be detected in thymus, lymph nodes, tonsils, and spleen, and also in specific regions of the brain, gut, and other non-lymphoid tissues. CD4 functions to initiate or augment the early phase of T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase, Lck. It may also function as an important mediator of direct neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcripts have been identified in this gene [RefSeq, July 2017].
Category | Antibody |
Supplier | ThermoFisher |
Application | FC |
Regulatory Status | RUO |
Immunogen | Human CD4 |
Host | Ms |
Clone Number | [S3.5] |
Genebank | CD4 |
Isotype | IgG2a |
Crossreactivity | Hu |
Clonality | Mab |
Format | Liquid; PBS; , with BSA, 10% sucrose and 0.1% sodium azide |
Working Dilution | Flow Cytometry (Assay-Dependent) |
Purity | purified |
Conjugation | PE/Texas Red |
Storage Conditions | 4° C, store in dark |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |