CD8 Monoclonal Antibody (3B5), Pacific Blue™


Catalog Number Pack Size List Price* Quantity
MHCD0828 500 µL 716,00 Add

* CHF, excl. 8.1% VAT and shipping costs


Product Description

For fluorochrome conjugated antibodies only, light exposure should be avoided. Use dim light during handling, incubation with cells, and prior to analysis. It is recommended that cells be analyzed within 18 hours of staining. If the reagent is being diluted, it is recommended that only the quantity to be used within one week be diluted. Each lot is tested by flow cytometry using human peripheral blood leukocytes (PBL). Based on this testing it is recommended that 5 µL of antibody be used per 1 x 10^6 cells in a 100 µL staining volume. Cluster of differentiation 8 (CD8), a type I transmembrane glycoprotein of the immunoglobulin family of receptors, plays an integral role in signal transduction, and T cell differentiation and activation. CD8 is predominantly expressed on T cells as a disulfide-linked heterodimer of CD8alpha and CD8beta, where it functions as a co-receptor, along with T cell receptor (TCR), for major histocompatibilty complex class I (MHC-I) molecules; whereas its counterpart, CD4, acts as a co-receptor for MHC-II molecules. CD8 exists on the cell surface, where the CD8alpha chain is essential for binding to MHC-I. CD8 is also expressed on a subset of T cells, NK cells, monocytes and dendritic cells as disulfide-linked homodimers of CD8alpha. Ligati

Category Antibody
Supplier ThermoFisher
Application FC
Regulatory Status RUO
Immunogen Recognizes the CD8 antigen
Host Ms
Clone Number [3B5]
Genebank CD8A
Isotype IgG2a
Crossreactivity Hu
Clonality Mab
Format Liquid; PBS; , with 4mg/mL BSA and 0.1% sodium azide
Concentration 0.25 mg/mL
Working Dilution Flow Cytometry (Assay-dependent)
Purity purified
Conjugation Pacific Blue
Storage Conditions 4° C
Tech. Data Sheet View datasheet
Link To Supplier https://www.thermofisher.com
Material Safety Data Sheet Download PDF