SSEA1 Monoclonal Antibody (VIMC6), Pacific Blue™
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
MHCD1528 | 500 µL | 750,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Our Pacific Blue™ dye is optimally excited by the violet laser and conjugates of this dye are strongly fluorescent even at neutral pH. Pacific Blue™ and Pacific Orange™ dye conjugates can be simultaneously excited at 405 nm and emit at 455 nm and 551 nm, respectively, facilitating two-color analysis. CD15 (Lewis X, Le(x); stage specific embryonic antigen-1, SSEA-1) is a trisacharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids, glycoproteins and proteoglycans of various cell types, e.g. granulocytes, mast cells, monocytes, macrophages, cells of gastric mucosa, nervous system or various tumour cells. There are several variants of Lewis x, such as sialyl-Lewis x or sulphated Lewis x. Cells with high surface expression of Le(x) antigen exhibit strong self-aggregation, based on calcium-dependent Le(x)-Le(x) interaction. This process is involved for example in embryo compaction or in autoaggregation of teratocarcinoma cells. Sialyl-Le(x) and its isomer sialyl-Le(a) are ligands of selectins. CD15 expression has been extensively used to confirm diagnosis of Hodgkin's disease.
Category | Antibody |
Supplier | ThermoFisher |
Application | FC |
Regulatory Status | RUO |
Immunogen | Human CD15 |
Host | Ms |
Clone Number | [VIMC6] |
Genebank | FUT4 |
Isotype | IgM |
Crossreactivity | Hu |
Clonality | Mab |
Format | Liquid; PBS; , with BSA and 0.1% sodium azide |
Working Dilution | Flow Cytometry (Assay-Dependent) |
Purity | Affinity chromatography |
Conjugation | Pacific Blue |
Storage Conditions | 4° C, store in dark |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |