NF-H Polyclonal Antibody
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
PA110002 | 50 µL | 662,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
This antibody reacts primarily with the phosphorylated axonal form of NF-H and shows some cross-reactivity with phosphorylated NF-M, which has similar phosphorylation sites to NF-H. Involved in the maintenance of neuronal caliber, neurofilaments are the intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. Like most other intermediate filament proteins (IFPs), the expression of the different neuronal IFPs is both tissue-specific and developmentally regulated. NF-H has an important role in mature axons and is involved in amyotrophic lateral sclerosis (ALS).
Category | Antibody |
Supplier | ThermoFisher |
Application | EL, ICC, IHC, WB |
Regulatory Status | RUO |
Immunogen | Native NF-H purified from bovine spinal cord. |
Host | Ck |
Genebank | NEFH |
Isotype | IgY |
Crossreactivity | Bo, Dg, Ho, Hu, Ms, Pg, Rt |
Clonality | Pab |
Format | Liquid; PBS; , with 0.02% sodium azide |
Working Dilution | Immunocytochemistry (1:20,000), ELISA (Assay-dependent), Western Blot (1:20,000), Immunohistochem... |
Conjugation | Unconjugated |
Storage Conditions | 4° C |
Disclaimer | Alternative CatNo: PA1-10002 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |