PP2A alpha Polyclonal Antibody


Catalog Number Pack Size List Price* Quantity
PA112393 100 µg 604,00 Add

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Product Description

In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunits have been identified, designated PP1, PP2A, PP2B (calcineurin) and PP2C. The PP2A family comprises subfamily members PP2A alpha and PP2A beta. An additional protein phosphatase catalytic subunit, PPX (also known as PP4) is a putative member of a novel PP family.

Category Antibody
Supplier ThermoFisher
Application ICC, IP, WB
Regulatory Status RUO
Research Field PROTEIN & CELL ANALYSIS
Immunogen Synthetic peptide.
Host Sh
Genebank PPP2CA
Isotype IgG
Crossreactivity Bo, Hu, Ms, Rt
Clonality Pab
Format Liquid; PBS; , with 0.08% sodium azide
Working Dilution Western Blot (1:1,000), Immunoprecipitation (Assay-dependent), Immunocytochemistry (1:100)
Purity Ammonium sulfate precipitation
Conjugation Unconjugated
Storage Conditions Freezer (-5 to -30 C)
Disclaimer Alternative CatNo: PA1-12393
Tech. Data Sheet View datasheet
Link To Supplier https://www.thermofisher.com
Shipping Details Ambient
Material Safety Data Sheet Download PDF