Acid Phosphatase 1 Polyclonal Antibody
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
PA112403 | 100 µg | 606,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Low molecular weight protein tyrosine phosphtases, including the human red cell phosphatase, HCPTP, are widely expressed cytosolic proteins of approximately 18 kDa that exist in distinct isoforms and are highly selective for phosphotyrosine over phosphoserine or phosphotyrosine. The HCPTP-A and HCPTP-B proteins expressed in human red cells and placenta are fast and slow forms of red cell acid phosphatase5. Like other tyrosine phosphatases, HCPTP is sensitive to inhibition by vanadate, and has a catalytic mechanism that involves formation of a cystinylphosphate intermediate6. The crystal structure of the bovine heart derived enzyme BHPTP shows a four-stranded central parallel b sheet with flanking a helices and an active site cysteine residue in the typical tyrosine phosphatase sequence context, CXXXXXR.
Category | Antibody |
Supplier | ThermoFisher |
Application | IP, WB |
Regulatory Status | RUO |
Immunogen | Recombinant human Protein Tyrosine Phosphatase expressed in E. coli. |
Host | Sh |
Genebank | ACP1 |
Isotype | IgG |
Crossreactivity | Bo, Hu, Ms, Rt |
Clonality | Pab |
Format | Liquid; PBS; , with 0.08% sodium azide |
Concentration | 0.5 mg/mL |
Working Dilution | Immunoprecipitation (Assay-dependent), Western Blot (Assay-dependent) |
Purity | Ammonium sulfate precipitation |
Conjugation | Unconjugated |
Storage Conditions | -20° C, Avoid Freeze/Thaw Cycles |
Disclaimer | Alternative CatNo: PA1-12403 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |