ACVR1 Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA112641 | 250 µg | 606,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
The TGF-beta superfamily of ligands exerts its biological activity by binding to heteromeric receptor complexes two types (I and II) of the serine/threonine kinases. ALK1, like the other type I receptors, contains a cysteine rich domain with conserved cysteine spacing in the extracellular region and a glycine and serine rich domain preceding the kinase domain. The reduced human ALK1 monomer has a calculated molecular mass of approximately 37.3 kDa. Due to glycoslyation, the recombinant human protein migrates as a 50-55 kDa protein in SDS-PAGE under reducing conditions. Human and mouse ALK1 share approximately 71% amino acid sequence identity in their extracellular domains. ALK1 is highly expressed in endothelial cells and other vascular tissues.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | WB |
| Regulatory Status | RUO |
| Immunogen | Recombinant protein corresponding to the extracellular domain of chicken ALK2. |
| Host | Sh |
| Genebank | ACVR1 |
| Isotype | IgG |
| Crossreactivity | Ck |
| Clonality | Pab |
| Format | Liquid; PBS; , with 0.08% sodium azide |
| Working Dilution | Western Blot (Assay-dependent) |
| Purity | Ammonium sulfate precipitation |
| Conjugation | Unconjugated |
| Storage Conditions | -20° C, Avoid Freeze/Thaw Cycles |
| Disclaimer | Alternative CatNo: PA1-12641 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
