HIF-2 alpha Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA116510 | 100 µL | 686,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Suggested positive control: Cos7 CoCl2-treated nuclear extract, PC12 nuclear extracts. HIF-2 alpha (Epas1) is a transcription factor involved in the induction of genes regulated by oxygen. HIF-2 alpha contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. It also regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of the lungs. Mutations in this gene are associated with erythrocytosis familial type 4.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ChIP, EL, FC, ICC, IHC, IP, WB |
| Regulatory Status | RUO |
| Immunogen | A peptide derived from the C-terminus of mouse/human HIF-2 alpha protein. |
| Host | Rb |
| Genebank | EPAS1 |
| Isotype | IgG |
| Crossreactivity | Fish, Hm, Hu, Ms, Primate, Sh, Rb, Rt, Reptile |
| Clonality | Pab |
| Format | Liquid; PBS; , with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Working Dilution | ChIP Assay (1:10-1:500), ELISA (1:100-1:2,000), Flow Cytometry (Assay-Dependent), Gel Shift (Assa... |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | -20°C |
| Disclaimer | Alternative CatNo: PA1-16510 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
