Aromatase Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA116532 | 100 µL | 738,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
This antibody is expected to react with equine (91%), bovine and rabbit (90%), porcine (83%), ovine, goat and canine (81%) based on sequence homology. Suggested positive control: antigen standard for CYP19A1 (transient overexpression lysate), human Fetal Temporal Lobe protein. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ICC, IHC, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | Synthetic peptide made to a C-terminal portion of the human aromatase protein sequence (between residues 400-502). |
| Host | Rb |
| Genebank | CYP19A1 |
| Isotype | IgG |
| Crossreactivity | Hu, Ms, Primate, Rb, Rt |
| Clonality | Pab |
| Format | Liquid; phosphate, tris citrate; pH 7-8, with 0.1% sodium azide |
| Concentration | 1.0 mg/mL |
| Working Dilution | Immunocytochemistry (1:100), Western Blot (1 µg/mL), Immunohistochemistry (Paraffin) (Assay-Depen... |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: PA1-16532 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Wet Ice |
| Material Safety Data Sheet | Download PDF |
