SR-BI Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA116788 | 100 µL | 662,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Suggested positive control: antigen standard for SCARB1 (transient overexpression lysate). High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. The SR-BI binds HDLs and mediates selective uptake of HDL cholesteryl ester. SR-BI binds HDL with high affinity, is expressed primarily in liver and nonplacental steroidgenic tissues, and mediates selective cholesterol uptake by a distinct mechanism. In mice, it seems that SR-BI plays a key role in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | FC, ICC, IHC, IP, N, WB |
| Regulatory Status | RUO |
| Immunogen | Synthetic peptide corresponding to a region within the residues 450-509 of mouse Scavenger Receptor-BI. |
| Host | Rb |
| Genebank | SCARB1 |
| Isotype | IgG |
| Crossreactivity | Hm, Hu, Mink, Ms, Primate, Pg, Rb, Rt |
| Clonality | Pab |
| Format | Liquid; PBS; , with 0.1% sodium azide |
| Concentration | 1 mg/mL |
| Working Dilution | Immunohistochemistry (Frozen) (2.5-5 µg/mL), Immunocytochemistry (1:50-1:1,000), Flow Cytometry (... |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | 4° C, do not freeze |
| Disclaimer | Alternative CatNo: PA1-16788 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
