MCP-2 Polyclonal Antibody


Catalog Number Pack Size List Price* Quantity
PA124664 25 µg 606,00 Add

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Product Description

The ND50 is approximately 2-5 µg/mL in the presence of 0.4 µg/mL of human MCP2, using the human monocyte chemotaxis assay. This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection.

Category Antibody
Supplier ThermoFisher
Application EL, N, WB
Regulatory Status RUO
Immunogen Purified, E. coli-derived, recombinant human MCP2.
Host Gt
Genebank CCL8
Isotype IgG
Crossreactivity Hu
Clonality Pab
Format Liquid; PBS; , with no preservative
Concentration 0.1 mg/mL
Working Dilution Neutralization (2-5 µg/mL), ELISA (0.5-1 µg/mL), Western Blot (0.1-0.2 µg/mL)
Purity Antigen affinity chromatography
Conjugation Unconjugated
Storage Conditions 4° C, do not freeze
Disclaimer Alternative CatNo: PA1-24664
Tech. Data Sheet View datasheet
Link To Supplier https://www.thermofisher.com
Material Safety Data Sheet Download PDF