IGF2 Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA124774 | 25 µg | 606,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
PA1-24774 detects IGF2 from mouse samples. The IGFs are mitogenic, polypeptide growth factors that stimulate the proliferation and survival of various cell types, including muscle, bone, and cartilage tissue in vitro. IGFs are predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGFs belong to the Insulin gene family, which also contains insulin and relaxin. The IGFs are similar to insulin by structure and function, but have a much higher growth-promoting activity than insulin. IGF-II expression is influenced by placenta lactogen, while IGF-I expression is regulated by growth hormone. Both IGF-I and IGF-II signal through the tyrosine kinase type I receptor (IGF-IR), but IGF-II can also signal through the IGF-II/Mannose-6-phosphate receptor. Mature IGFs are generated by proteolytic processing of inactive precursor proteins, which contain N-terminal and C-terminal propeptide regions.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | EL, N, WB |
| Regulatory Status | RUO |
| Immunogen | purified recombinant mouse insulin-like growth factor II, expressed in E. coli |
| Host | Gt |
| Genebank | IGF2 |
| Isotype | IgG |
| Crossreactivity | Ms |
| Clonality | Pab |
| Format | Liquid; PBS; , with 0.1% BSA, 5% trehelose and no preservative |
| Concentration | 0.1 mg/mL |
| Working Dilution | ELISA (0.5-1 µg/mL), Western Blot (0.1-0.2 µg/mL), Neutralization (1.5-4.5 µg/mL) |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Disclaimer | Alternative CatNo: PA1-24774 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
