IFN beta Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA124778 | 25 µg | 602,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
PA1-24778 has been successfully used in Western blot procedures, where a band of approximately 224 kDa is predicted to be detected. Type I Interferons (IFN-alpha/beta) are produced primarily in response to viral infection by Natural IFN-producing cells (IPCs) as part of the host immune response. IFNs can also inhibit the development of tumors. IFN-beta binding results in the activation of the tyrosine kinases Jak1 and Tyk2, phosphorylation of members of the STAT family of transcription factors, and the transcription and expression of the immune response genes. More recently, several members of the toll-like receptor (TLR) family were found to stimulate the production IFN-beta. IFN-beta is currently used clinically for treatment of tumors, infections and multiple sclerosis.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | N, WB |
| Regulatory Status | RUO |
| Immunogen | Purified, recombinant human IFN-beta, expressed in E. coli. |
| Host | Gt |
| Genebank | IFNB1 |
| Isotype | IgG |
| Crossreactivity | Hu |
| Clonality | Pab |
| Format | Liquid; PBS; , with no preservative |
| Concentration | 0.1 mg/mL |
| Working Dilution | Western Blot (0.1-2 µg/mL), Neutralization (0.05-0.20 µg/mL) |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Disclaimer | Alternative CatNo: PA1-24778 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
