IFN gamma Polyclonal Antibody
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
PA124782 | 25 µg | 658,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
PA1-24782 will not react with human. The Neutralization Dose 50 (ND50) for anti-rat IFNG is approximately 0.08 to 0.2 µg/mL in the presence of 2.5 ng/mL of recombinant rat IFNG, measuring the protection of mouse L-929 cells from the lytic effect of the virus. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. IFN gamma (Interferon gamma, Type II interferon) is a macrophage activation factor, and immune interferon that is produced primarily by T-lymphocytes and natural killer cells in response to antigens, mitogens, Staphylococcus enterotoxin B, phytohemaglutanin and other cytokines. IFN gamma is a dimeric protein consisting of two 146 amino acid subunits. IFN gamma is a glycoprotein that exists, functionally, as a homodimer of approximately 45 kDa. On SDS-PAGE, IFN gamma appears as a combination of 25, 20 and minor 15.5 kDa bands as a result of differential glycosylation. The biological activity of the IFN gamma homodimer is highly species specific. Human IFN gamma does not show cross-reactivity with mouse. IFN gamma function includes the following: antiviral activity, tumor antiproliferative activity, induction of class I and II MHC, macrophage activation, and enhanced immunoglobulin secretion by B lymphocytes. IFN gamm
Category | Antibody |
Supplier | ThermoFisher |
Application | IHC, N, WB |
Regulatory Status | RUO |
Immunogen | Purified, recombinant rat IFNG, expressed in E. coli. |
Host | Gt |
Genebank | IFNG |
Isotype | IgG |
Crossreactivity | Ms, Rt |
Clonality | Pab |
Format | Liquid; PBS; , with 5% trehalose and no preservative |
Concentration | 0.2 mg/mL |
Working Dilution | Inhibition Assays (0.08-0.20 µg/mL), Western Blot (0.1-0.2 µg/mL), Neutralization (0.08-0.20 µg/m... |
Purity | Antigen affinity chromatography |
Conjugation | Unconjugated |
Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Disclaimer | Alternative CatNo: PA1-24782 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |