GDNF Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA124827 | 200 µg | 656,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Neutralization: The ND50 is 2.6 µg/mL. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. GDNF is a glycosylated, disulfide-bonded homodimer molecule. It was first discovered as a potent survival factor for midbrain dopaminergic neurons and was then shown to rescue these neurons in animal models of Parkinson's disease. GDNF is about 100 times more efficient survival factor for spinal motor neurons than the neurotrophins. GDNF is a neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | N |
| Regulatory Status | RUO |
| Immunogen | Recombinant, full length human GDNF protein expressed in E. coli. |
| Host | Gt |
| Genebank | GDNF |
| Isotype | IgG |
| Crossreactivity | Hu |
| Clonality | Pab |
| Format | Liquid; PBS; , with no preservative |
| Concentration | 1 mg/mL |
| Working Dilution | Neutralization (2.6 µg/mL), Inhibition Assays (2.6 µg/mL) |
| Purity | Protein G |
| Conjugation | Unconjugated |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Disclaimer | Alternative CatNo: PA1-24827 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
