PDGF-BB Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA124834 | 25 µg | 660,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Neutralization: The ND50 is 0.025-0.200 µg/mL. The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | EL, N, WB |
| Regulatory Status | RUO |
| Immunogen | Recombinant, full length human protein expressed in E. coli. |
| Host | Gt |
| Genebank | PDGFB |
| Isotype | IgG |
| Crossreactivity | Hu |
| Clonality | Pab |
| Format | Liquid; PBS; pH 7.4, with 5% trehalose and no preservative |
| Concentration | 0.1 mg/mL |
| Working Dilution | Western Blot (0.1-0.2 µg/mL), Inhibition Assays (0.025-0.200 µg/mL), ELISA (0.5-1 µg/mL), Neutral... |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Disclaimer | Alternative CatNo: PA1-24834 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
