Glucocorticoid Receptor Polyclonal Antibody
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
PA128366 | 100 µL | 656,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. Glucocorticoid Receptor (NR3C1) is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. Glucocorticoid Receptor can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Glucocorticoid Receptor is expressed in the heart, detected in left and right atria, left and right ventricles, aorta, apex, intraventricular septum, and atrioventricular node as well as whole adult and fetal heart. Alternate splicing, the use of at least three different promoters, and alternate translation initiation sites result in several transcript variants encoding the same protein or different isoforms, but the full-length nature of some variants has not been determined. Mutations in the Glucocorticoid Receptor gene are a cause of glucocorticoid resistance, or cortisol, resistance.
Category | Antibody |
Supplier | ThermoFisher |
Application | WB |
Regulatory Status | RUO |
Immunogen | Peptide consisting of amino acids 150-175 of squirrel monkey glucocorticoid receptor coupled to diptheria toxoid. This sequence is identical in human glucocorticoid receptor except for 2 amino acid... |
Host | Sh |
Genebank | NR3C1 |
Isotype | IgG |
Crossreactivity | Hu, Primate |
Clonality | Pab |
Format | Liquid; PBS; , with no preservative |
Working Dilution | Western Blot (1:500-1:1,000) |
Purity | purified |
Conjugation | Unconjugated |
Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Disclaimer | Alternative CatNo: PA1-28366 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |