Collagen II Polyclonal Antibody, Biotin


Catalog Number Pack Size List Price* Quantity
PA128531 50 µg 664,00 Add

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Product Description

The reactivity of the antibody is greatly diminished under denaturing and reducing conditions. COL2A1 is the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia.

Category Antibody
Supplier ThermoFisher
Application EL, IHC, IP, WB
Regulatory Status RUO
Immunogen Collagen Type II from adult human knee cartilage and bovine nasal cartilage
Host Rb
Genebank COL2A1
Isotype IgG
Crossreactivity Bo, Hu, Ma, Ms, Rt
Clonality Pab
Format Liquid; 0.02M potassium phosphate; pH 7.2, with 0.15M NaCl and 0.01% sodium azide
Concentration 1 mg/mL
Working Dilution Immunoprecipitation (1:100), ELISA (1:10,000-1:50,000), Western Blot (1:5,000-1:10,000), Immunohi...
Purity Antigen affinity chromatography
Conjugation Biotin
Storage Conditions Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Disclaimer Alternative CatNo: PA1-28531
Tech. Data Sheet View datasheet
Link To Supplier https://www.thermofisher.com
Material Safety Data Sheet Download PDF