GLI3 Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA129595 | 50 µg | 604,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Expected to cross react with chicken (100% identity), human (100% identity), mouse, (94% identity), Xenopus laevis (100% identity) due to sequence homology. This gene encodes a protein which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | EL, IHC, WB |
| Regulatory Status | RUO |
| Immunogen | synthetic peptide NEDESPGQTYHRERRNA-C conjugated to KLH, corresponding to amino acids 41-57 of Human GLI3. |
| Host | Rb |
| Genebank | GLI3 |
| Isotype | IgG |
| Crossreactivity | Avian, Dg, Ck, Chimpanzee, Hu, Ms, Primate, Xenopus, Zebrafish |
| Clonality | Pab |
| Format | Liquid; 0.02M potassium phosphate; pH 7.2, with 0.15M NaCl and 0.01% sodium azide |
| Concentration | 1 mg/mL |
| Working Dilution | Western Blot (1:500-1:2,000), ELISA (1:6000-1:30,000), Immunohistochemistry (Paraffin) (0.5 mg/ml... |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Disclaimer | Alternative CatNo: PA1-29595 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
