ICAM-1 Polyclonal Antibody, Biotin
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
PA129968 | 250 µL | 632,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
PA1-29968 detects ICAM1 from human, rhesus and cynomolgus monkey, baboon, an chimpanzee samples. ICAM-1 (CD54) is an 85-110 kDa single-chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. ICAM-1 has 7 potential N-linked glycosylation sites and shares considerable amino acid sequence homology with ICAM-3 (CD50) and ICAM-2 (CD102). ICAM-1 binds to integrins of type CD11a/CD18 (leukocyte adhesion molecule, LFA-1), or CD11b/CD18 (Mac-1) and is exploited by Rhinovirus as a receptor. ICAM-1 is expressed by activated endothelial cells and detected on epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils, with lower levels that increase upon inflammation. ICAM-1 is also detected in some carcinoma and melanoma cells. Soluble ICAM-1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes.
Category | Antibody |
Supplier | ThermoFisher |
Application | IHC, IP, WB |
Regulatory Status | RUO |
Immunogen | Full length protein (Human) |
Host | Rb |
Genebank | ICAM1 |
Isotype | IgG |
Crossreactivity | Baboon, Chimpanzee, Hu, Primate |
Clonality | Pab |
Format | Liquid; PBS; , with 0.1% BSA and 0.02% sodium azide |
Concentration | 0.1 mg/mL |
Working Dilution | Immunoprecipitation (Assay-dependent), Immunohistochemistry (Frozen) (Assay-dependent), Western B... |
Purity | IgG fraction |
Conjugation | Biotin |
Storage Conditions | 4° C |
Disclaimer | Alternative CatNo: PA1-29968 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |