LIMK1 Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA131026 | 50 µg | 632,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
PA1-31026 detects LIM Kinase from human samples. There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is likely to be a component of an intracellular signaling pathway and may be involved in brain development. LIMK1 hemizygosity is implicated in the impaired visuospatial constructive cognition of Williams syndrome.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ICC, WB |
| Regulatory Status | RUO |
| Immunogen | synthetic peptide ETYRRGESGLPAHPEVPD, corresponding to amino acids 630-647 of Human LIM Kinase. |
| Host | Rb |
| Genebank | LIMK1 |
| Isotype | IgG |
| Crossreactivity | Chimpanzee, Hu, Ms, Primate |
| Clonality | Pab |
| Format | Liquid; 0.02M potassium phosphate; pH 7.2, with 0.15M NaCl and 0.01% sodium azide |
| Concentration | 1 mg/mL |
| Working Dilution | Western Blot (1:500-1:2,000), Immunocytochemistry (1:200) |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Disclaimer | Alternative CatNo: PA1-31026 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
