SR-BI Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA131405 | 100 µL | 748,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
PA1-31405 detects SR-BI from rat, mouse, human samples. High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. The SR-BI binds HDLs and mediates selective uptake of HDL cholesteryl ester. SR-BI binds HDL with high affinity, is expressed primarily in liver and nonplacental steroidgenic tissues, and mediates selective cholesterol uptake by a distinct mechanism. In mice, it seems that SR-BI plays a key role in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | FC, ICC, IHC, IP, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | A C-terminal peptide containing residues from mouse Scavenger Receptor-BI (within residues 450-509). |
| Host | Rb |
| Genebank | SCARB1 |
| Isotype | IgG |
| Crossreactivity | Hm, Hu, Ms, Mustelid, Primate, Rb, Rt |
| Clonality | Pab |
| Format | Liquid; PBS; , with 0.1% sodium azide |
| Concentration | 1.0 mg/mL |
| Working Dilution | Immunohistochemistry (Paraffin) (2.5-5 µg/mL), Western Blot (1:500-1:5,000), Flow Cytometry (1:10... |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Cold Room (2 to 8 C) |
| Disclaimer | Alternative CatNo: PA1-31405 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Ambient |
| Material Safety Data Sheet | Download PDF |
