TFEB Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA131552 | 50 µg | 680,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Expected to cross react with human due to sequence homology. Positive control of NIH-3T3 lysate suggested. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. The Transcription factor EB (TFEB) is a member in the basic helix-loop-helix leucine zipper superfamily of transcription factors that is translocated in a subset of renal tumors. Recent studies have shown that lysosomal biogenesis is regulated by TFEB, which is in turn regulated by the mammalian target of rapamycin (mTOR) complex 1. Other evidence suggests that TFEB coordinates the major steps of the autophagic pathway by driving the expression of autophagy and lysosomal genes.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ChIP, ICC, WB |
| Regulatory Status | RUO |
| Immunogen | Peptide with sequence ASRIGLRMQLMRE, from N Terminus of the protein sequence according to NP_009093 |
| Host | Gt |
| Genebank | TFEB |
| Isotype | IgG |
| Crossreactivity | Hu, Rt |
| Clonality | Pab |
| Format | Liquid; TBS; pH 7.3, with 0.5% BSA and 0.02% sodium azide |
| Concentration | 0.5 mg/mL |
| Working Dilution | Western Blot (0.3-1 µg/mL), ChIP Assay (Assay-dependent), Immunocytochemistry (5 µg/ml) |
| Purity | Ammonium sulfate precipitation/Affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Disclaimer | Alternative CatNo: PA1-31552 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
