AP2 alpha Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA131776 | 50 µg | 656,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. TFAP2A is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. TFAP2A is the only AP-2 protein required for early morphogenesis of the lens vesicle.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | EL, IP, WB |
| Regulatory Status | RUO |
| Immunogen | synthetic peptide AVSKGDGMRGLAC, corresponding to amino acids 3 - 14 of Human AP2 alpha. |
| Host | Gt |
| Genebank | TFAP2A |
| Isotype | IgG |
| Crossreactivity | Dg, Ck, Chimpanzee, Hu, Ms, Primate, Rt |
| Clonality | Pab |
| Format | Liquid; 0.02M potassium phosphate; pH 7.2, with 0.15M NaCl and 0.01% sodium azide |
| Working Dilution | Western Blot (1:500-1:2,000), Immunoprecipitation (1:100), ELISA (1:5,000-1:20,000) |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Disclaimer | Alternative CatNo: PA1-31776 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
