ABCA1 Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA132129 | 100 µL | 720,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. Mutations in the ABCA1 gene (ATP-binding cassette transporter 1) have been reported in Tangier disease (TD). TD is an autosomal recessive disorder characterized by an absence of plasma HDL, cholesterol ester depositing in the reticulo-endothelial system and deviations in cellular lipid trafficking. ABCA1 mediates the apo-A1 associated export of cholesterol and phospholipids from the cell. It is expressed on the plasma membrane and the Golgi complex, and is regulated by cholesterol flux. Regulation of the cholesterol flux between HDL and macrophages is competitive between ABCA1 and SR-BI.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ChIP, FC, ICC, IHC, IP, WB |
| Regulatory Status | RUO |
| Immunogen | synthetic peptide corresponding to amino acids 1100-1300 of Human ABCA 1. |
| Host | Rb |
| Genebank | ABCA1 |
| Isotype | IgG |
| Crossreactivity | Dg, Ck, Hm, Hu, Ms, Mustelid, Pg, Rt |
| Clonality | Pab |
| Format | Liquid; PBS; , with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Working Dilution | Immunohistochemistry (Paraffin) (1:200), Western Blot (1:500-1:1,000), Immunocytochemistry (1:100... |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Disclaimer | Alternative CatNo: PA1-32129 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
