Histone H2B Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA141058 | 100 µg | 676,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
This peptide sequence is 100% conserved between multiple species including human, mouse, rat, dog, chimpanzee, cow, chicken, duck, zebrafish, and drosophila. Suggested positive control: Jurkat, PBMC. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The nucleosomes wrap further and compact DNA into chromotin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones play a central role in transciption regulation, DNA repair, DNA replication, and chromosomal stability. H2B has a broad antibacterial activity.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ChIP, IHC, WB |
| Regulatory Status | RUO |
| Immunogen | Synthetic peptide corresponding to amino acids 111-125 of human histone H2B [GenBank no. CAI19747.1] |
| Host | Rb |
| Genebank | H2B |
| Isotype | IgG |
| Crossreactivity | Dg, Ck, Drosophila, Hu, Ma, Ms, Rt, Zebrafish |
| Clonality | Pab |
| Format | Liquid; PBS; , with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Working Dilution | Western Blot (2 µg/mL), Immunohistochemistry (Paraffin) (10 µg/mL), ChIP Assay (1.5 µg per millio... |
| Purity | Protein G |
| Conjugation | Unconjugated |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Disclaimer | Alternative CatNo: PA1-41058 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
