LexA Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA14966 | 50 µL | 678,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
PA1-4966 detects LexA protein in E.coli and yeast samples. PA1-4966 has been successfully used in Western blot, immunoprecipitation and immunohistochemical procedures. It is specific for the ~23 kDa LexA protein. PA1-4966 immunogen is a highly purified recombinant full size LexA protein. Store at -20ºC. E. coli LexA protein inhibits the transcription of the genes belonging to the SOS regulon that are related to DNA repair and cell division by recognizing and binding to the SOS-box sequence. LexA‘s self-protease activity is promoted by RecA protein which, responding to DNA damage, is activated by its binding to single-strand DNA accumulated in the cells. It is cleaved into two fragments and loses its function as a repressor. As the result, the expression of genes belonging to the SOS regulon is induced, and mutagenic activity in the cells are enhanced.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ChIP, IHC, IP, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | Full size LexA recombinant protein. |
| Host | Rb |
| Isotype | IgG |
| Crossreactivity | Bacteria, Yeast |
| Clonality | Pab |
| Format | Liquid; whole serum; , with 0.05% sodium azide |
| Working Dilution | ChIP Assay (Assay-dependent), Immunohistochemistry (Assay-dependent), Immunoprecipitation (Assay-... |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: PA1-4966 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Wet Ice |
| Material Safety Data Sheet | Download PDF |
