Salmonella Polyclonal Antibody

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Product Description

PA1-7244 detects Salmonella. This antibody is polyvalent for Salmonella "O & H" antigens. The antiserum is unabsorbed and does crossreact with related Enterobacteriaceae. PA1-7244 has been successfully used in ELISA, and immunofluorescence procedures. The PA1-7244 immunogen is a mixture of S. enteriditis, S. typhimurium, and S. heidelburg. Recommended short term (less than 6 months) storage is 2-8ºC. For longer term storage, aliquot and freeze at -20ºC. The genus Salmonella is a member of the family Enterobacteriaceae. The genus is composed of Gram negative bacilli that are facultative and flagellated (motile). Salmonellae possess 3 major surface antigens; the H or flagellar antigen (phase 1 and 2), the O or somatic antigen (part of the LPS moiety) and the Vi or capsular antigen (referred to as K in other Enterobacteriaceae). Salmonellae also possess the LPS endotoxin characteristic of Gram negative bacteria. This LPS is composed of an O polysaccharide (O antigen) an R core and the endotoxic inner Lipid A. Endotoxins evoke fever and can activate complement, kinin and clotting factors.