Salmonella Polyclonal Antibody, FITC

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Product Description

The PA1-73020 antibody reacts with Salmonella species and crossreacts with related enterobacteriaceae. PA1-73020 has been successfully used in Immunofluorescence applications. Acetone fixation of the antigen source is recommended prior to staining. The PA1-73020 antibody was raised against a mixture of S. enteriditis, S. typhimurium & S. heidelburg (O & H antigens). The genus Salmonella is a member of the family Enterobacteriaceae. The genus is composed of Gram negative bacilli that are facultative and flagellated (motile). Salmonellae possess 3 major surface antigens; the H or flagellar antigen (phase 1 and 2), the O or somatic antigen (part of the LPS moiety) and the Vi or capsular antigen (referred to as K in other Enterobacteriaceae). Salmonellae also possess the LPS endotoxin characteristic of Gram negative bacteria. This LPS is composed of an O polysaccharide (O antigen) an R core and the endotoxic inner Lipid A. Endotoxins evoke fever and can activate complement, kinin and clotting factors.