H4ac pan-acetyl (K5,K8,K12,K16) Polyclonal Antibody


Catalog Number Pack Size List Price* Quantity
PA184526 100 µL 854,00 Add

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Product Description

Rabbit anti Histone H4 (Acetylated) antibody was raised against the tetra-acetylated form of histone H4 and recognizes acetylated isoforms of histone H4. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Category Antibody
Supplier ThermoFisher
Application ChIP, EL, ICC, IP, WB
Regulatory Status RUO
Research Field PROTEIN & CELL ANALYSIS
Immunogen KLH-conjugated peptide acetylated at lysines 5,8,12,16: NSGRGAcKGGAcKGLGAcKGGAAcKRHYCC
Host Rb
Genebank H4-16
Isotype IgG
Crossreactivity Multi, Hu, Ms, Rt
Clonality Pab
Format Liquid; whole serum; , with <0.1% sodium azide
Working Dilution Western Blot (1/800), ELISA (1/400), Immunoprecipitation (Assay-dependent), ChIP Assay (Assay-dep...
Conjugation Unconjugated
Storage Conditions Freezer (-5 to -30 C)
Disclaimer Alternative CatNo: PA1-84526
Tech. Data Sheet View datasheet
Link To Supplier https://www.thermofisher.com
Shipping Details Wet Ice
Material Safety Data Sheet Download PDF