Decorin Polyclonal Antibody
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
PA185833 | 1 mL | 608,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Sheep anti human decorin antibody recognizes the C-terminal region of human bone proteoglycan II, also known as decorin, PG-S2 or PG40. Decorin is a member of the small, leucine-rich proteoglycan (SLRP) family along with biglycan. Found in the interterritorial region of cartilage, decorin interacts with collagen and other matrix proteins to regulate the cartilaginous matrix. It has been shown to interact with fibronectin, thrombospondin, C1q, epidermal growth factor receptor (EGFR), and TGF-b. It is believed that decorin also plays a role in the cell cycle of chondrocytes. The decorin neoepitope fragment has a sequence of PKTLQE, and is generated by MMP-3 or ADAMTS-4 cleavage at Glu154-Leu155 of decorin core protein.
Category | Antibody |
Supplier | ThermoFisher |
Application | EL, WB |
Regulatory Status | RUO |
Immunogen | Synthetic peptide, KLH conjugated, corresponding to residues C(316) V Y V R S A I Q L G N Y K(329) of Bone Proteoglycan II Precursor. |
Host | Sh |
Genebank | DCN |
Isotype | IgG |
Crossreactivity | Bo, Ck, Hu |
Clonality | Pab |
Format | Liquid; PBS; pH 7.2, with 0.09% sodium azide |
Concentration | 5 mg/mL |
Working Dilution | ELISA (Assay-dependent), Western Blot (Assay-dependent) |
Purity | Protein G |
Conjugation | Unconjugated |
Storage Conditions | 4°C or -20°C if preferred |
Disclaimer | Alternative CatNo: PA1-85833 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |