Decorin Polyclonal Antibody


Catalog Number Pack Size List Price* Quantity
PA185833 1 mL 608,00 Add

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Product Description

Sheep anti human decorin antibody recognizes the C-terminal region of human bone proteoglycan II, also known as decorin, PG-S2 or PG40. Decorin is a member of the small, leucine-rich proteoglycan (SLRP) family along with biglycan. Found in the interterritorial region of cartilage, decorin interacts with collagen and other matrix proteins to regulate the cartilaginous matrix. It has been shown to interact with fibronectin, thrombospondin, C1q, epidermal growth factor receptor (EGFR), and TGF-b. It is believed that decorin also plays a role in the cell cycle of chondrocytes. The decorin neoepitope fragment has a sequence of PKTLQE, and is generated by MMP-3 or ADAMTS-4 cleavage at Glu154-Leu155 of decorin core protein.

Category Antibody
Supplier ThermoFisher
Application EL, WB
Regulatory Status RUO
Immunogen Synthetic peptide, KLH conjugated, corresponding to residues C(316) V Y V R S A I Q L G N Y K(329) of Bone Proteoglycan II Precursor.
Host Sh
Genebank DCN
Isotype IgG
Crossreactivity Bo, Ck, Hu
Clonality Pab
Format Liquid; PBS; pH 7.2, with 0.09% sodium azide
Concentration 5 mg/mL
Working Dilution ELISA (Assay-dependent), Western Blot (Assay-dependent)
Purity Protein G
Conjugation Unconjugated
Storage Conditions 4°C or -20°C if preferred
Disclaimer Alternative CatNo: PA1-85833
Tech. Data Sheet View datasheet
Link To Supplier https://www.thermofisher.com
Material Safety Data Sheet Download PDF