HDAC1 Polyclonal Antibody, Alexa Fluor™ 647
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA1860A647 | 50 µL | 578,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
PA1860A647 detects histone deacetylase 1 (HDAC1) from human, mouse, rat, hamster and canine tissues and cells. The PA1860A647 immunogen is a synthetic peptide corresponding to residues C E(467) E K P E A K G V K E E V K L A(482) of human HDAC1. This immunizing peptide (Cat. # PEP-069) is available for use in neutralization and control experiments. Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. HDAC1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, HDAC1 deacetylates p53 and modulates its effect on cell growth and apoptosis.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ICC |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | Synthetic peptide corresponding to residues C E(467) E K P E A K G V K E E V K L A(482) of human HDAC1 |
| Host | Rb |
| Genebank | HDAC1 |
| Isotype | IgG |
| Crossreactivity | Dg, Hm, Hu, Ms, Rt |
| Clonality | Pab |
| Format | Liquid; PBS; pH 7.4, with 1mg/mL BSA and 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Working Dilution | Immunocytochemistry (1-10 µg/mL) |
| Purity | Antigen affinity chromatography |
| Conjugation | Alexa Fluor 647 |
| Storage Conditions | Cold Room (2 to 8 C) |
| Disclaimer | Alternative CatNo: PA1-860-A647 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Ambient |
| Material Safety Data Sheet | Download PDF |
