Calreticulin Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA1902A | 100 µL | 632,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
PA1-902A detects calreticulin from canine, hamster, human, mouse and rat tissues. PA1-902A has been successfully used in Western blot, immunocytochemistry and immunofluorescene procedures. By Western blot, this antibody detects an ~60-66 kDa protein representing calreticulin. PA1-902A immunizing peptide corresponds to amino acid residues 24-43 from mouse calreticulin. PA1-902A immunizing peptide (Cat. # PEP-018) is available for use in neutralization and control experiments. Calr or Calreticulin is a calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. Calr, a lectin, interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Calr also interacts with with the DNA-binding domain of NR3C1 and mediates its nuclear export. It may also be involved in maternal gene expression regulation and oocyte maturation via the regulation of calcium homeostasis.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ICC, WB |
| Regulatory Status | RUO |
| Immunogen | Synthetic Peptide: K(24) E Q F L D G D A W T N R W V E S K H K(43). |
| Host | Ck |
| Genebank | CALR |
| Isotype | IgY |
| Crossreactivity | Dg, Hm, Hu, Ms, Rt |
| Clonality | Pab |
| Format | Liquid; , with 1mg/mL BSA and 0.05% sodium azide |
| Concentration | 1.1 mg/mL |
| Working Dilution | Immunocytochemistry (Assay-dependent), Western Blot (1:500-1:2,000) |
| Purity | Antigen affinity chromatography |
| Conjugation | Unconjugated |
| Storage Conditions | -20° C, Avoid Freeze/Thaw Cycles |
| Disclaimer | Alternative CatNo: PA1-902A |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
